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BIOMAT 2010

BIOMAT 2010

Author: Rubem P. Mondaini

Publisher: World Scientific

ISBN: 9789814343435

Category: Science

Page: 398

View: 359

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This volume contains the selected contributed papers of the BIOMAT 2010 International Symposium which has been organized as a joint conference with the 2010 Annual Meeting of the Society for Mathematical Biology (http: //www.smb.org) by invitation of the Director Board of this Society. The works presented at Tutorial and Plenary Sessions by expert keynote speakers have been also included. This book contains state-of-the-art articles on special research topics on mathematical biology, biological physics and mathematical modelling of biosystems; comprehensive reviews on interdisciplinary areas written by prominent leaders of scientific research groups. The treatment is both pedagogical and sufficiently advanced to enhance future scientific research

BIOMAT 2010

BIOMAT 2010

Author: Rubem P Mondaini

Publisher: World Scientific

ISBN: 9789814460675

Category: Science

Page: 412

View: 889

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This volume contains the selected contributed papers of the BIOMAT 2010 International Symposium which has been organized as a joint conference with the 2010 Annual Meeting of the Society for Mathematical Biology (http://www.smb.org) by invitation of the Director Board of this Society. The works presented at Tutorial and Plenary Sessions by expert keynote speakers have been also included. This book contains state-of-the-art articles on special research topics on mathematical biology, biological physics and mathematical modelling of biosystems; comprehensive reviews on interdisciplinary areas written by prominent leaders of scientific research groups. The treatment is both pedagogical and sufficiently advanced to enhance future scientific research. Contents:MorphologyMolecular BiophysicsMathematical EpidemiologyPopulation DynamicsPopulation BiologyTheoretical ImmunologyComputational BiologyMathematical Aspects of BioprocessesPopulation GeneticsSystems Biology Readership: Mathematicians, biologists, physicists; graduate and undergraduate students interested in biomathematics. Keywords:Mathematical Biology;Biological Physics;Mathematical Modelling of Biosystems

Pedigree Analysis in R

Pedigree Analysis in R

Author: Magnus Dehli Vigeland

Publisher: Academic Press

ISBN: 9780128245606

Category: Law

Page: 184

View: 141

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Pedigree Analysis in R gives an introduction to the theory of relatedness and covers a range of applications in forensic and medical genetics. The book's material was developed through teaching courses on genetic relatedness, pedigree analysis and R, and offers insights from a decade of research activities in forensic and medical genetics. The R code in the book uses the ped suite, a unified collection of packages for pedigree analysis, developed by the author. All code examples are given in full, allowing accurate reproduction of figures and results. At the end of each chapter, a selection of exercises encourages the reader to explore further and perform their own analyses. Introduction to the theory of genetic relatedness, richly illustrated with classic and novel examples In-depth case studies including kinship testing, pedigree reconstruction, linkage analysis and clinical segregation analysis Easy-to-follow R code with explanations Based on the ped suite packages for pedigree analysis in R Suitable for R users at all levels, including complete beginners Exercises after each chapter

Recent Progress in the Genetic Epidemiology of Cancer

Recent Progress in the Genetic Epidemiology of Cancer

Author: Henry T. Lynch

Publisher: Springer Science & Business Media

ISBN: 9783642759932

Category: Medical

Page: 162

View: 933

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The discipline of genetic epidemiology pertains to the vertical transmission of the susceptibility (predisposition) to a complex disease in a structured population. This statement meets halfway 1 the broad definitiongiven by N. E. Morton and S. c. Chung in 1978 2 and the concise one given by M. -C. King et al. in 1984. 1t pinpoints the fundamental genetic hypothesis, namely, the existence of an inherited condition that predisposes an individual to a specific disease, and the corresponding subject ofinvestigation, the family. Thus, the genetic epidemiological situation consists of three basic elements: (l) the genealogical structure, (2) the mode of inherit ance (i. e. , the "genetic model") for the trait of interest, and (3) the observable phenotypes of susceptibility. It is clear that genetic epidemiology is a research field posi tioned at the intersection of molecular genetics, population gen etics, and clinical genetics. Perhaps the genealogical tree should be its central element: it evidences something forgotten in mole cular genetics, namely the relationships, and associations with probabilistic and statistical concepts from population genetics. It offers a structure and a "history" for those clinicians studying familial diseases who are searching for genetic determinants of susceptibility. The genetic epidemiologist begins his analysis with a point on this genealogical tree, namely the proband, and attempts to carry out (nonrandom) "ascertainment sampling" by using a strategy that depends on the form and dimension (extended pedigrees versus nuclear families) of the tree.

Using Variation Theory to Enhance Students' Capability in Solving Pedigree Problems

Using Variation Theory to Enhance Students' Capability in Solving Pedigree Problems

Author: Tat-Ho Lam

Publisher: Open Dissertation Press

ISBN: 1361369728

Category:

Page:

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This dissertation, "Using Variation Theory to Enhance Students' Capability in Solving Pedigree Problems" by Tat-ho, Lam, 林達豪, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: This thesis reports on a learning study that employed variation theory to enhance a domain-specific generic-capability pedigree analysis of Hong Kong secondary five students so as to help them develop their capability to solve pedigree problems. Pedigree analysis is a study of inheritance in genetics, which includes the deduction of dominant and recessive characters. The literature and local examination reports suggested that solving pedigree problems is difficult for students, as the process of deduction demands conceptual understanding and use of scientific language. Three biology teachers participated in this learning study using variation theory. Teachers shifted the focus of lesson observation from teaching performance to student learning, to how students deduced the dominant character from pedigree problems, which was the object of learning. To explore the effectiveness of such teaching and learning to solve pedigree problems through different patterns of variation, two cycles of learning study were conducted in two senior biology classes. Results showed that students were more able to deduce the dominant character with relevant genetic principles by experiencing the variations. Both conceptual understanding and scientific language are critical aspects of solving pedigree problems. This study also suggests that explanatory scientific writing needs to be broken down into different components and then differentiated patterns of variation designed to let students discern those components and their relationships; in that way their writing can be 'scaffolded' in a stepwise manner rather than giving them the whole writing framework at once. However, the identification of critical features and patterns of variation and their relevance to the object of learning should be considered carefully and explored further. DOI: 10.5353/th_b5387974 Subjects: Study and teaching (Secondary) - Genetics - China - Hong Kong

Social Evolution and Inclusive Fitness Theory

Social Evolution and Inclusive Fitness Theory

Author: James A.R. Marshall

Publisher: Princeton University Press

ISBN: 9780691183336

Category: Science

Page: 216

View: 254

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Social behavior has long puzzled evolutionary biologists, since the classical theory of natural selection maintains that individuals should not sacrifice their own fitness to affect that of others. Social Evolution and Inclusive Fitness Theory argues that a theory first presented in 1963 by William D. Hamilton—inclusive fitness theory—provides the most fundamental and general explanation for the evolution and maintenance of social behavior in the natural world. James Marshall guides readers through the vast and confusing literature on the evolution of social behavior, introducing and explaining the competing theories that claim to provide answers to questions such as why animals evolve to behave altruistically. Using simple statistical language and techniques that practicing biologists will be familiar with, he provides a comprehensive yet easily understandable treatment of key concepts and their repeated misinterpretations. Particular attention is paid to how more realistic features of behavior, such as nonadditivity and conditionality, can complicate analysis. Marshall highlights the general problem of identifying the underlying causes of evolutionary change, and proposes fruitful approaches to doing so in the study of social evolution. Social Evolution and Inclusive Fitness Theory describes how inclusive fitness theory addresses both simple and complex social scenarios, the controversies surrounding the theory, and how experimental work supports the theory as the most powerful explanation for social behavior and its evolution.

Racehorse Breeding Theories

Racehorse Breeding Theories

Author: Frank J. Mitchell

Publisher: The Russell Meerdink Company Ltd.

ISBN: 9780929346755

Category: Sports & Recreation

Page: 325

View: 369

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"Here, in one volume, is a wide and varied assessment of the major breeding systems or theories, as well as the history and background of each. The writers give the reader all the necessary information they need to implement the theory and make it part of a breeding program. They also verify the relative scientific validity of the theories and various approaches to breeding" -- publisher website (April 2007).

Population Genetics and Microevolutionary Theory

Population Genetics and Microevolutionary Theory

Author: Alan R. Templeton

Publisher: John Wiley & Sons

ISBN: 9781118504369

Category: Science

Page: 768

View: 781

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Population Genetics and Microevolutionary Theory Explore the fundamentals of the biological implications of population genetic theory In the newly revised Second Edition of Population Genetics and Microevolutionary Theory, accomplished researcher and author Alan R. Templeton delivers a fulsome discussion of population genetics with coverage of exciting new developments in the field, including new discoveries in epigenetics and genome-wide studies. The book prepares students to successfully apply population genetics analytical tools by providing a solid foundation in microevolutionary theory. The book emphasizes that population structure forms the underlying template upon which quantitative genetics and natural selection operate and is a must-read for future population and evolutionary geneticists and those who wish to work in genetic epidemiology or conservation biology. You’ll learn about a wide array of topics, including quantitative genetics, the interactions of natural selection with other evolutionary forces, and selection in heterogeneous environments and age-structured populations. Appendices that cover genetic survey techniques and probability and statistics conclude the book. Readers will also benefit from the inclusion of: A thorough introduction to population genetics, including the scope of the subject, its premises, and the Hardy-Weinberg Model of Microevolution An exploration of systems of mating, including a treatment of the use of runs of homozygosity to show pedigree inbreeding in distant ancestors A practical discussion of genetic drift, including the use of effective sizes in conservation biology (with a discussion of African rhinos as an example) A concise examination of coalescence, including a treatment of the infinite sites model Perfect for graduate students in genetics and evolutionary biology programs and advanced undergraduate biology majors, Population Genetics and Microevolutionary Theory will also earn a place in the libraries of students taking courses in conservation biology, human genetics, bioinformatics, and genomics.

New Frontiers in Graph Theory

New Frontiers in Graph Theory

Author: Yagang Zhang

Publisher: BoD – Books on Demand

ISBN: 9789535101154

Category: Computers

Page: 528

View: 476

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Nowadays, graph theory is an important analysis tool in mathematics and computer science. Because of the inherent simplicity of graph theory, it can be used to model many different physical and abstract systems such as transportation and communication networks, models for business administration, political science, and psychology and so on. The purpose of this book is not only to present the latest state and development tendencies of graph theory, but to bring the reader far enough along the way to enable him to embark on the research problems of his own. Taking into account the large amount of knowledge about graph theory and practice presented in the book, it has two major parts: theoretical researches and applications. The book is also intended for both graduate and postgraduate students in fields such as mathematics, computer science, system sciences, biology, engineering, cybernetics, and social sciences, and as a reference for software professionals and practitioners.